Insulin resistance (IR) is a condition characterised by resistance to the effects of insulin at a cellular level. Muscle and adipose tissue require increasing greater amounts of insulin to transfer sugars from the bloodstream. Higher levels of pancreatic insulin synthesis are required to maintain normal blood levels and, therefore both fasting and post-prandial glucose levels rise. Increasing HOMA scores reflect this. Untreated insulin resistance will become diabetes and require medical intervention and ongoing treatment.
Insulin Resistance is calculated from both the fasting insulin and fasting glucose results to create the HOMA score (homoeostasis model assessment of insulin resistance).